Research area

Natural Products & Phytochemical Pharmacology

Extracts and phytochemicals tested for antioxidant, anti-inflammatory, hepatoprotective and anticancer activity.

Cytochrome P450 14alpha-sterol demethylase (left) and NADPH:adrenodoxin reductase with adrenodoxin (right). — David Goodsell, RCSB PDB · CC BY 4.0

Overview

Natural-product research is common in Pakistan and internationally, and reviewers increasingly expect extract standardisation, dose justification and appropriate positive controls. Planning these early prevents the most common rejections.

Questions we can help you answer

How should my extract be prepared and standardised?
Which positive controls and doses are defensible?
Which assays will show the mechanism I claim?

Methods we advise on

Extraction and fractionation planning
Antioxidant assays
Cytotoxicity and apoptosis
Hepatoprotection models
Formulation evaluation

Please note

Activity in a laboratory model does not establish that a herbal product is safe or effective for people.

Relevant services

This painting shows a cross-section through an Escherichia coli cell. The characteristic two-membrane cell wall of gram-negative bacteria is shown in green, with many lipopolysaccharide chains extending from the surface and a network of cross-linked peptidoglycan strands between the membranes — Goodsell · RCSB PDB · CC BY

Wet-Lab Strategy & Experimental Research Support

Experimental planning, assay design, troubleshooting and interpretation from a scientist with long bench experience. Hands-on work is coordinated only with qualified external laboratories.

For:: Postgraduate students designing or troubleshooting experiments
Lead:: Scientific Lead

Explore service

This painting includes three types of filaments that make up the cytoskeleton: a microtubule (the largest), an intermediate filament (the knobby one), and two actin filaments (the smallest ones). The large blue molecules are ribosomes , busy in their task of synthesizing proteins — Goodsell · RCSB PDB · CC BY

Scientific & Research Consulting

Sharpen the research question, choose a defensible design and plan the work before time and reagents are spent.

For:: Postgraduate researchers and early-career scientists
Lead:: Scientific Lead

Explore service

Structures of nanobodies (green) bound to SARS-CoV-2 spike protein (magenta). — Goodsell · RCSB PDB · CC BY

Computational Biology & Bioinformatics

Docking, network pharmacology and reproducible analysis workflows — with honest limits on what in silico results mean.

For:: MPhil and PhD researchers adding an in silico chapter
Lead:: Scientific Lead

Explore service

Tell us what you’re working on.

Send a short, confidential summary. We reply with an initial scope assessment, and you agree deliverables, timeline and price before anything starts.

Discuss your research